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Those included: lysine methylations on the C-terminus of the sequence or detected in peptides with acidic residues (attainable artifacts of methyl esterification of the carboxylic group) and peptides with deamidation on the C-terminal arginine (tryptic cleavage after a deamidated residue have been lately proven as a highly unlikely event forty one ). These figures are extremely significantly in favour of lysine aspirin nasal remedy: p = 0.019, 0.007, 0.004 respectively.
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